Pathology and Oncology Research

Original Research

Published on 21 Nov 2025

Valosin containing protein (VCP/p97) expression in laryngeal squamous cell carcinoma: clinical evaluation and implications for targeted therapy

Inga M. C. Seuthe
Hanna C. Hunsicker-Biederbeck
Markus Ruwe
Julius Knierer
Eric Ehrke-Schulz
Eren Erdogan
Sabine Eichhorn
Jonas J.-H. Park

Pathology and Oncology Research

doi 10.3389/pore.2025.1612202

Original Research

Published on 13 Nov 2025

Comprehensive genomic profiling for homologous recombination deficiency guides PARP inhibitor therapy recommendations in ovarian cancer

Alp Inci
Isabell Witzel
Holger Moch
Sepehr Rahmani-Khajouei
Martin Zoche
Eleftherios Pierre Samartzis

Pathology and Oncology Research

doi 10.3389/pore.2025.1612266

Original Research

Published on 07 Nov 2025

Trop2 expression, p16 expression status, and histologic subtype in carcinoma of the uterine cervix

Grit Gesine Ruth Hiller
Benjamin Wolf
Mirjam Forberger
Annekathrin Freude
Christine Elisabeth Brambs
Svenja Droste
Lars-Christian Horn
Anne Kathrin Höhn

Pathology and Oncology Research

doi 10.3389/pore.2025.1612252

Original Research

Published on 30 Oct 2025

Examination of histopathological growth patterns of liver metastases in a retrospective, consecutive, single-center, cohort study

Anita Sejben
Parsa Abbasi
Boglárka Pósfai
Tamás Lantos

Pathology and Oncology Research

doi 10.3389/pore.2025.1612161

Original Research

Published on 28 Oct 2025

Synergistic changes in bystander CD8 and conventional CD4 T cells during neoadjuvant chemoimmunotherapy for non-small cell lung cancer reveal treatment response

Li Wu
Liying Yang
Jian Sun
Miaoqing Zhao
Jiaxiao Geng
Fanghan Cao
Qianhui Chen
Yushan Yan
Hao Yang
Xiaorong Sun

Pathology and Oncology Research

doi 10.3389/pore.2025.1612229

Case Report

Published on 28 Oct 2025

Case Report: From teratoma to adenocarcinoma: molecular insights into somatic-type malignancy in testicular germ cell tumors - two case reports and review of the literature

Tímea Rozsvai
Boglárka Pósfai
László Torday
Emőke Borzási
György Lázár
Judit Oláh
Bence Radics
István Előd Király
István Papos
Márton Balázsfi

Pathology and Oncology Research

doi 10.3389/pore.2025.1612227

Review

Published on 20 Oct 2025

Circulating tumor cells: indicators of cancer progression, plasticity and utility for therapies

Tamás Richárd Linkner
Zsófia Brigitta Nagy
Alexandra Kalmár
Eszter Farkas
Fruzsina Bányai
Nikolett Szakállas
István Takács
Béla Molnár

Pathology and Oncology Research

doi 10.3389/pore.2025.1612181

Original Research

Published on 25 Sep 2025

Two B or not two B; the question of bendamustine dosing in low grade lymphoma

Eszter Földi
Ádám Wiedemann
Szabolcs Svorenj
Virág Réka Szita
András Dávid Tóth
Ilona Tárkányi
Ágnes Fehér
Ágnes Kárpáti
Laura Horváth
Gergely Szombath

Pathology and Oncology Research

doi 10.3389/pore.2025.1612195

Mini Review

Published on 23 Sep 2025

Modelling metastasis in a dish: in vitro approaches for studying breast cancer progression

Irem Duman
Verena Pichler

Pathology and Oncology Research

doi 10.3389/pore.2025.1612179

Original Research

Published on 22 Sep 2025

The prognostic potential of circulating biomarkers for sarcoma patients with pleural dissemination

Hannah Schwab
Stéphane Collaud
Sebastian Bauer
Uta Dirksen
Dirk Theegarten
Fabian Doerr
Konstantinos Grapatsas
Natalie Baldes
Clemens Aigner
Servet Bölükbas

Pathology and Oncology Research

doi 10.3389/pore.2025.1612133

Original Research

Published on 12 Sep 2025

The value of morphology: osteoclast-like cells in soft tissue tumours

Ali Al Khader
Christian Seghetti
Fatine Oumlil
Anna Tollit
Roberto Tirabosco
Fernanda Amary
Paul O’Donnell
Adrienne M. Flanagan

Pathology and Oncology Research

doi 10.3389/pore.2025.1612175

Original Research

Published on 11 Sep 2025

Relationship between qualitative and quantitative parameters of three-dimensional computed tomography, EGFR gene mutation, and ALK gene rearrangement in GGO-associated lung adenocarcinoma and their prognostic value

Xinyan Liu
Yi Ren
Zihang Fei
Qingmei Shi
Li Lu

Pathology and Oncology Research

doi 10.3389/pore.2025.1612081

Case Report

Published on 09 Sep 2025

Case Report: Genomic profiling in an invasive solid papillary carcinoma patient with liver metastasis and a history of invasive lobular carcinoma

Xuan Wang
Feng Zhu
Hui Wang
Shaojie Sheng
Tongbing Chen

Pathology and Oncology Research

doi 10.3389/pore.2025.1612129

Original Research

Published on 13 Aug 2025

B7-H3: a consistent marker in metastatic colorectal cancer with potential for targeted treatment

Julia M. Ott
Verena Gassenmaier
Michael Bitzer
Christian M. Schürch
Jonas S. Heitmann
Ilona Hagelstein

Pathology and Oncology Research

doi 10.3389/pore.2025.1612186

Review

Published on 04 Aug 2025

Conjunctival melanoma: comprehensive insights into clinical features, genetic alterations, and modern treatment approaches

Snježana Kaštelan
Danijela Mrazovac Zimak
Luka Ivić
Antonela Gverović Antunica
Tamara Nikuševa-Martić

Pathology and Oncology Research

doi 10.3389/pore.2025.1612085

Original Research

Published on 01 Aug 2025

Application of TRPS1 in ER-negative or low expression distant metastatic breast carcinoma

Runze Zhang
Jing Liu
Lei Jiang
Zhiqiang Lang

Pathology and Oncology Research

doi 10.3389/pore.2025.1612138

Original Research

Published on 28 Jul 2025

Early-stage resectable non-small cell lung cancer in Hungary

Gabriella Gálffy
Réka Hécz
Réka Bujdosó
Eszter Gáspár
Réka Korompay
Judit Hoffer
Szilvia Szécsényi
Celia Blasszauer
Dániel Reibl
Erika Tóth

Pathology and Oncology Research

doi 10.3389/pore.2025.1612152

Original Research

Published on 23 Jul 2025

MtDNA copy number enrichment is associated with poor prognosis and eosinophilic morphology in clear cell renal cell carcinoma

Sarah Bellal
Cyrielle Rolley
Jeremy Richard
Nolwenn Bounaix
Vincent Le Corre
Marie-Christine Copin
Odile Blanchet
Pierre Bigot
Vincent Procaccio
Céline Bris

Pathology and Oncology Research

doi 10.3389/pore.2025.1612172

Case Report

Published on 07 Jul 2025

Case Report: Toxic tubulointerstitial nephropathy with lipofuscin deposition – the potential cause of occupational Bisphenol-A exposition

László Bidiga
Tamás Csonka
Gábor Méhes
Csilla Markóth
Dávid Hutkai
János Mátyus

Pathology and Oncology Research

doi 10.3389/pore.2025.1612046

Original Research

Published on 07 Jul 2025

Diagnostic challenges of rarely well-differentiated adenocarcinoma of the stomach

Tian Qin
Yong Wang
Zebin Xiao
Lili Ma
Chao Fan
Chongyu Zhu
Luqiao Luo
Qingling Zhang
Chao Liu

Pathology and Oncology Research

doi 10.3389/pore.2025.1612163

Original Research

Published on 01 Jul 2025

The implications of abnormal signal patterns of break-apart FISH probes used in the diagnosis of bone and soft tissue tumours

Hongtao Ye
Fitim Berisha
Evie Rowles
Emani Munasinghe
Christopher Davies
Akanksha Farswan
Nischalan Pillay

Pathology and Oncology Research

doi 10.3389/pore.2025.1612142

Brief Research Report

Published on 26 Jun 2025

Novel FRMD6::PTH chimera in tumorous bone lesion carrying a t(4;11;14;12)(q35;p15;q22;q13)

Ioannis Panagopoulos
Kristin Andersen
Isabel Lloret
Ludmila Gorunova
Ingvild Lobmaier

Pathology and Oncology Research

doi 10.3389/pore.2025.1612096

Original Research

Published on 05 Jun 2025

Comparison of intraoperative frozen section consultation and hysterectomy characteristics in patients diagnosed with EIN in endometrial biopsies

Hasan Volkan Ege
Bilal Esat Temiz
Alp Usubutun
Deniz Ates Ozdemir
Muhammed Onur Atakul
Murat Cengiz
Utku Akgor
Derman Basaran
Murat Gultekin
Mehmet Coskun Salman

Pathology and Oncology Research

doi 10.3389/pore.2025.1612039

Original Research

Published on 02 Jun 2025

Low-grade oncocytic tumor of the kidney—a clinical, pathological, and next generation sequencing-based study of 20 tumors

Alex Jenei
Boglárka Pósfai
Borbála Dénes
Áron Somorácz
Gertrud Forika
Attila Fintha
Zsófia Mészáros
Noémi Kránitz
Tamás Micsik
Kornélia Veronika Eizler

Pathology and Oncology Research

doi 10.3389/pore.2025.1612150

2,951 Publications

volumes

Volume 31 - 2025

Valosin containing protein (VCP/p97) expression in laryngeal squamous cell carcinoma: clinical evaluation and implications for targeted therapy

Comprehensive genomic profiling for homologous recombination deficiency guides PARP inhibitor therapy recommendations in ovarian cancer

Trop2 expression, p16 expression status, and histologic subtype in carcinoma of the uterine cervix

Examination of histopathological growth patterns of liver metastases in a retrospective, consecutive, single-center, cohort study

Synergistic changes in bystander CD8 and conventional CD4 T cells during neoadjuvant chemoimmunotherapy for non-small cell lung cancer reveal treatment response

Case Report: From teratoma to adenocarcinoma: molecular insights into somatic-type malignancy in testicular germ cell tumors - two case reports and review of the literature

Circulating tumor cells: indicators of cancer progression, plasticity and utility for therapies

Two B or not two B; the question of bendamustine dosing in low grade lymphoma

Modelling metastasis in a dish: in vitro approaches for studying breast cancer progression

The prognostic potential of circulating biomarkers for sarcoma patients with pleural dissemination

The value of morphology: osteoclast-like cells in soft tissue tumours

Relationship between qualitative and quantitative parameters of three-dimensional computed tomography, EGFR gene mutation, and ALK gene rearrangement in GGO-associated lung adenocarcinoma and their prognostic value

Case Report: Genomic profiling in an invasive solid papillary carcinoma patient with liver metastasis and a history of invasive lobular carcinoma

B7-H3: a consistent marker in metastatic colorectal cancer with potential for targeted treatment

Conjunctival melanoma: comprehensive insights into clinical features, genetic alterations, and modern treatment approaches

Application of TRPS1 in ER-negative or low expression distant metastatic breast carcinoma

Early-stage resectable non-small cell lung cancer in Hungary

MtDNA copy number enrichment is associated with poor prognosis and eosinophilic morphology in clear cell renal cell carcinoma

Case Report: Toxic tubulointerstitial nephropathy with lipofuscin deposition – the potential cause of occupational Bisphenol-A exposition

Diagnostic challenges of rarely well-differentiated adenocarcinoma of the stomach

The implications of abnormal signal patterns of break-apart FISH probes used in the diagnosis of bone and soft tissue tumours

Novel FRMD6::PTH chimera in tumorous bone lesion carrying a t(4;11;14;12)(q35;p15;q22;q13)

Comparison of intraoperative frozen section consultation and hysterectomy characteristics in patients diagnosed with EIN in endometrial biopsies

Low-grade oncocytic tumor of the kidney—a clinical, pathological, and next generation sequencing-based study of 20 tumors