AUTHOR=Székely Réka , Suhai Ferenc I., Karlinger Kinga , Baksa Gábor , Szabaczki Bence , Bárány László , Pölöskei Gergely , Rácz Gergely , Wagner Ödön , Merkely Béla , Ruttkay Tamás 

TITLE=Human Cadaveric Artificial Lung Tumor-Mimic Training Model

JOURNAL=Pathology and Oncology Research

VOLUME=Volume 27 - 2021

YEAR=2021

URL=https://www.por-journal.com/journals/pathology-and-oncology-research/articles/10.3389/pore.2021.630459

DOI=10.3389/pore.2021.630459

ISSN=1532-2807

ABSTRACT=Introduction: An important phase in surgical training is gaining experience in real human anatomical situations. When a cadaver is available it may complement the various artificial practice models. However, it is often necessary to supplement the characteristics of the cadavers with a simulation of a tumor. Our objective was to develop an easy-to-create, realistic artificial tumor-mimic model for peripheral lung tumor resection practice.
Methods: In our work we injected barium sulphate enriched silicone suspension into 10 isolated, non-fixed lungs of human cadavers, through the puncture of the visceral pleura. Four lesions - apical, hilar and two peripheral - were created in each of ten specimens. After fixation CT scans were obtained and analyzed. The implanted tumor-mimics were examined after anatomical preparation and slicing. Also performed CT-guided percutaneous puncture was also performed to create the lesions in situ in two lungs of human cadavers.
Results: Analyzing the CT data of 10 isolated lungs, out of 40 lesions, 34 were nodular (85.0%) and in the nodular group 5 were spiculated (12.5%). Satellite lesions were formed in 2 cases (5.0%). Relevant outflow into vessels or airway occurred in 5 lesions (12.5%). Reaching the surface of the lung occured in 11 lesions (27.5%). The tumor-mimics were elastic and adhered well to the surrounding tissue. The two lesions, implanted via percutaneous puncture, both were nodular and one also showed lobulated features.
Conclusions: Our artificial tumor-mimics were easy to create, varied in shape and size, and with percutaneous implantation the lesions provide a model for teaching every step of a surgical procedure.